In the first expansion of Diablo 4, Vessel of Hatred DLC, a lot of new content has been added, such as new mechanics and new classes. But the most important thing for players to spend time researching is Runewords system, because it is not in the previous base game, and it can add a huge power boost to your character and gear.

In Runewords system, the most important thing must be Runes. It is scattered all over the game, but you need to look carefully at it. This guide will introduce you to some methods to obtain these precious Runes and their specific uses.

How To Farm Runes?

There are many ways to get more runes in Diablo 4 Vessel of Hatred, some of which are very easy, but some are very difficult. Although most methods have a sense of randomness, there are ways if you want to guarantee a certain rune.

World Bosses Drops

The easiest and most common way to get Runes is by defeating World Bosses, as they appear from chests or loot provided by enemies. Because of the randomness of farming, you should try to farm in places with a high density of enemies, such as The Pit or Helltides.

Or you can challenge some higher difficulty enemies, such as directly challenging the enemies in Torment Difficulty Tiers. But it should be noted that you need to use Diablo 4 Gold in advance to make your build strong enough so that there will be no waste of resources or materials, and it is possible to get numerous Runes at once.

Alternatively, you can also try to challenge some enemies with a lot of excellent loot in the new Kurast Undercity. They are also very worthwhile.

Crafting Runes

In addition to the above random methods of obtaining runes, you can also obtain some specific runes through crafting. You need to use three runes of the same rarity and craft different types of rarer runes at Jeweler.

Of course, you can also use the crafting system at Jeweler and the runes you have to craft other Diablo 4 Items, such as Mythic Uniques that can provide you with very large buffs and very rare Resplendent Sparks.

This means that you can get multiple Resplendent Sparks in this expansion and the current season of the base game of Diablo 4 - from Tormented Bosses, from Lilith, from the reputation system, and from this crafting system.

Trade With Other Players

In addition to the above two self-reliant methods, you can also trade the runes you want with other players, which will make you more sure that you can get the runes you want. But here, I need to remind you that trading is risky, so please always be vigilant.

What Are Runes For?

There are tons of runes available in Diablo 4 Vessel of Hatred DLC, and they are divided into two categories: Runes of Invocation and Runes of Ritual. When you combine one of the two rune types together, these runes form Runewords. You can then insert them into any weapon, item, or gear piece with two slots.

Rune of Ritual can generate resources called Offerings, which are used to trigger Runes of Invocation. This means that you need to have enough Offering for Runes of Invocation to work, and the stronger Invocation, the more Offering you need.

The opposite is also true: the harder Rune of Ritual is to obtain, the more Offering they will generate, and the stronger the effect. So in short, only high-level or rare Rune of Ritual will make the entire Runewords have the strongest effect, which means that the build you put in will also become stronger.

The following is the number of Offerings each Rune of Ritual can provide and the number of Offerings each Runes of Invocation requires. You can choose the corresponding rune combination based on this list, and the attributes of the items you want to equip.

Runes Of Ritual

• Ahu - 10
• Bac - 50
• Cem - 50
• Cir - 25
• Feo - 1000
• Kaa - 2
• Lith - 25
• Moni - 10
• Neo - 300
• Noc - 5
• Poc - 2
• Tam - 25
• Ur - 10
• Xol - 150
• Yax - 100
• Yul - 50
• Zan - 150

Runes Of Ritual

• Ceh - 100
• Eom - 100
• Gar - 25
• Jah - 500
• Kry - 500
• Lac - 800
• Lum - 5
• Met - 100
• Mot - 150
• Ner - 700
• Ohm - 500
• Ono - 25
• Qax - 400
• Qua - 400
• Tal - 100
• Teb - 100
• Tec - 100
• Thul - 400
• Ton - 25
• Tun - 100
• Tzic - 250
• Vex - 400
• Wat - 100
• Xal - 200
• Xan - 700
• Yom - 500
• Zec - 200

There are currently three rarities of Runes - Magic Runes, Rare Runes and Legendary Runes. And each will increase the power and ability of Runewords according to its rarity. But here you need to be reminded that no matter how many slots you have in your weapon or other items, you can only equip a maximum of two Runewords at a time, which is 4 Runes.

These are the methods to obtain and use runes in Diablo 4 Vessel of Hatred DLC. You may need to try this combination of Runewords yourself, or you can also find combinations shared by other players in player communities such as IGGM Discord. Most importantly, you will have a chance to get some Diablo 4 Gold or other rare items. Have fun playing the game!